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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDPK1
All Species:
18.48
Human Site:
Y126
Identified Species:
33.89
UniProt:
O15530
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15530
NP_002604.1
556
63152
Y126
I
K
E
N
K
V
P
Y
V
T
R
E
R
D
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537000
560
63701
Y130
I
K
E
N
K
V
P
Y
V
T
R
E
R
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2A0
559
63740
Y129
I
K
E
N
K
V
P
Y
V
T
R
E
R
D
V
Rat
Rattus norvegicus
O55173
559
63591
Y129
I
K
E
N
K
V
P
Y
V
T
R
E
R
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518589
320
36424
Chicken
Gallus gallus
Q6U1I9
432
48872
L59
H
P
E
V
Q
S
I
L
K
I
S
Q
P
Q
E
Frog
Xenopus laevis
Q6GPN6
434
49096
L61
P
S
E
V
Q
S
I
L
N
I
S
P
P
Q
E
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
L60
H
P
E
V
Q
S
I
L
N
L
T
P
P
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W0V1
836
94060
I291
R
E
R
K
Q
D
Y
I
K
R
E
R
E
V
M
Honey Bee
Apis mellifera
XP_394208
537
61368
S126
E
R
L
Y
F
V
L
S
Y
A
K
N
G
E
L
Nematode Worm
Caenorhab. elegans
Q9Y1J3
636
71898
K118
M
D
A
I
I
R
E
K
N
I
L
T
Y
L
S
Sea Urchin
Strong. purpuratus
XP_786576
539
61612
Y128
I
R
E
K
K
E
K
Y
V
L
R
E
K
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12236
1081
121642
V224
R
Q
K
K
V
K
Y
V
S
I
E
K
T
A
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93.3
N.A.
94.8
95.3
N.A.
52.1
28.6
28
27.5
N.A.
32.5
54.1
32.5
58
Protein Similarity:
100
N.A.
N.A.
95
N.A.
96.2
96.4
N.A.
54.6
44
43.8
43.3
N.A.
44.1
66.1
52.2
70.3
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
0
6.6
6.6
6.6
N.A.
0
6.6
0
53.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
0
20
13.3
13.3
N.A.
20
33.3
6.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
8
0
0
0
0
0
0
0
31
8
% D
% Glu:
8
8
62
0
0
8
8
0
0
0
16
39
8
16
16
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
39
0
0
8
8
0
24
8
0
31
0
0
0
0
0
% I
% Lys:
0
31
8
24
39
8
8
8
16
0
8
8
8
0
0
% K
% Leu:
0
0
8
0
0
0
8
24
0
16
8
0
0
8
16
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
31
0
0
0
0
24
0
0
8
0
0
0
% N
% Pro:
8
16
0
0
0
0
31
0
0
0
0
16
24
0
0
% P
% Gln:
0
8
0
0
31
0
0
0
0
0
0
8
0
24
0
% Q
% Arg:
16
16
8
0
0
8
0
0
0
8
39
8
31
0
0
% R
% Ser:
0
8
0
0
0
24
0
8
8
0
16
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
31
8
8
8
0
0
% T
% Val:
0
0
0
24
8
39
0
8
39
0
0
0
0
8
39
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
16
39
8
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _